{"product_id":"superdex-200-increase-10-300-gl","title":"Superdex 200 Increase SEC column, 10\/300 GL","description":"\u003cp\u003eOverview\u003cbr\u003e\r\nSuperdex™ 200 Increase size exclusion (also referred to as gel filtration) chromatography columns are well suited for high-resolution analysis and small-scale purification of monoclonal antibodies (mAb) and other biomolecules with Mr~ 10 000 to ~ 600 000.\u003cbr\u003e\r\n\u003cbr\u003e\r\n•Enhanced performance: improved resolution and runtime compared to predecessor Superdex™ 200.\u003cbr\u003e\r\n•Very high resolution: small bead size and narrow particle size distribution provide high resolution, for high protein purity.\u003cbr\u003e\r\n•High flow rates: rigid beads give excellent pressure\/flow properties.\u003cbr\u003e\r\n\u003cbr\u003e\r\n“Increase”: Cytiva's size exclusion chromatography columns\u003cbr\u003e\r\nSuperdex™ 200 Increase is a next-generation, dextran-agarose composite matrix for SEC. With smaller and more rigid beads than their predecessors, Superdex™ Increase columns deliver higher resolution purification in shorter run times.\u003cbr\u003e\r\n\u003cbr\u003e\r\nA range of pre-packed columns is available to suit a variety of preparative and analytical applications (Table 1-1).\u003cbr\u003e\r\n\u003cbr\u003e\r\nSelectivity for small-scale purification and analysis of monoclonal antibodies\u003cbr\u003e\r\nSuperdex™ 200 Increase has a selectivity curve optimized for excellent resolution of antibodies and macromolecules within the range Mr ~ 100 000 to ~ 300 000. It is well suited for detection and separation of antibody monomers, dimers, and aggregates present in monoclonal antibody preparations.\u003cbr\u003e\r\n\u003cbr\u003e\r\nThe outstanding resolving power of this resin facilitates protein characterization, including analysis of antibody size variants, assessment of membrane protein size homogeneity, and the study of protein-protein interactions.\u003cbr\u003e\r\n\u003cbr\u003e\r\nSuperdex™ 200 and Superose™ 6 analysis ranges are complementary\u003cbr\u003e\r\nSuperdex™ 200 Increase is optimized to give high resolution separation for proteins with molecular weights in the range Mr ~ 100 000 to ~ 300 000. Superose™ 6 Increase provides a complementary fractionation range, resolving very large protein complexes and macromolecules that Superdex 200 Increase cannot separate.\u003cbr\u003e\r\n\u003cbr\u003e\r\nCleaning-in-place (CIP) capabilities\u003cbr\u003e\r\nThis agarose-based resin is alkali-resistant and supports cleaning-in-place (CIP) procedures. This capability allows the same column to be used for different proteins, with minimal risk of carry-over between samples.\u003cbr\u003e\r\n\u003cbr\u003e\r\nRegular cleaning can also increase column lifetime.\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"Default Title","offer_id":53660026274083,"sku":"CYTI28990944","price":4064.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0597\/5896\/9012\/files\/28990944.jpg?v=1788470126","url":"https:\/\/onelab.co.nz\/products\/superdex-200-increase-10-300-gl","provider":"Onelab","version":"1.0","type":"link"}